ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,473,538, issued on Nov. 18, was assigned to Roche Sequencing Solutions Inc. (Pleasanton, Calif.).
"DP04 polymerase variants" was invented by Mark Stamatios Kokoris (Bothell, Wash.), Marc Prindle (Seattle), Jack Chase (Seattle), Robert Busam (Seattle), Michael Kovarik (Seattle), Salka Keller (Shoreline, Wash.), Megan Murt (Seattle) and Greg Thiessen (Seattle).
According to the abstract* released by the U.S. Patent & Trademark Office: "Recombinant DPO4-type DNA polymerase variants with amino acid substitutions that confer modified properties upon the polymerase for improved single molecule sequencing applications are provided. Such properties may include enhanced binding and incorporat...