US Patent Issued to Roche Sequencing Solutions on Jan. 20 for "Methods for removal of adaptor dimers from nucleic acid sequencing preparations" (California Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,529,100, issued on Jan. 20, was assigned to Roche Sequencing Solutions Inc. (Pleasanton, Calif.).

"Methods for removal of adaptor dimers from nucleic acid sequencing preparations" was invented by Arkadiusz Bibillo (Cupertino, Calif.) and Randall W. Davis (Pleasanton, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Sequencing adaptors and methods are provided for preparation of polynucleotides for sequencing. The sequencing adaptors contain a portion of a recognition sequence for a methyl-dependent endonuclease. Unwanted adaptor dimers that form during ligation of adaptors to target polynucleotides produce a complete restriction sequence and are cl...