ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,704,504, issued on Aug. 11, was assigned to Roche Diagnostics Operations Inc. (Indianapolis).

"Derivatization of beta-lactam antibiotics as calibrators/ISTD in massspec measurements" was invented by Florian Huber (Penzberg, Germany), Thomas Scheidt (Penzberg, Germany) and Gaston Hubertus Maria Vondenhoff (Penzberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a complex comprising an antibiotic substance and a nucleophilic derivatization reagent, compositions comprising the complex, kits comprising complex or composition, as well as uses of the complex or composition."

The patent was filed on May 16, 2022, under Applic...