ALEXANDRIA, Va., April 15 -- United States Patent no. 12,601,001, issued on April 14, was assigned to Roche Diagnostics Operations Inc. (Indianapolis).

"Stabilization of NADPH or NADH in ammonia detection assays" was invented by Steffen Bossert-Reuther (Mannheim, Germany), Rolf Nagel (Mannheim, Germany) and Silvia Rettig (Mannheim, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure deals with the biochemistry of reagents useful in the detection of ammonia in liquid samples. Specifically, the present disclosure is directed to a technical improvement of an enzyme-based test for ammonia that can be used for analysis of plasma samples taken from patients in clinical settings, among oth...