ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,617, issued on March 3, was assigned to Riptide Bioscience Inc. (Vallejo, Calif.).

"Methods for modulating macrophage activity" was invented by Jesse Jaynes (Auburn, Ala.), Henry Wilfred Lopez (Napa, Calif.), George R. Martin (Rockville, Md.), Clayton Yates (Auburn, Ala.) and Balasubramanyam Karanam (Auburn, Ala.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods according to certain embodiments include contacting a macrophage with a mannose receptor (CD206) binding agent in a manner sufficient to modulate activity of the macrophage. Methods for converting a phenotype of a macrophage from an M2 phenotype to an M1 phenotype are also provided. Met...