ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,706, issued on Jan. 27, was assigned to RIKEN (Wako, Japan) and RACTHERA Co. LTD. (Tokyo).
"Method for maturation of retinal tissue containing continuous epithelium" was invented by Hideya Sakaguchi (Wako, Japan), Yoshiki Sasai (Wako, Japan), Mototsugu Eiraku (Wako, Japan), Daiki Nukaya (Tokyo) and Atsushi Kuwahara (Hyogo, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a method for maintaining a continuous epithelial structure of a retinal tissue including culturing the retinal tissue in a medium comprising a methyl group donor or a substrate of the methyl group donor at a concentration at which cell differentiat...