US Patent Issued to Rigel Pharmaceuticals on June 16 for "Inhibitors of ret" (Massachusetts Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,655,128, issued on June 16, was assigned to Rigel Pharmaceuticals Inc. (South San Francisco, Calif.).

"Inhibitors of ret" was invented by Jason D. Brubaker (Cambridge, Mass.), Joseph L. Kim (Wayland, Mass.), Kevin J. Wilson (Cambridge, Mass.), Douglas Wilson (Ayer, Mass.) and Lucian V. DiPietro (Gloucester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are compounds that inhibit wild-type RET and its resistant mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions. In certain embodiments, the compounds have Formula IIa or IIb:"

The patent was filed on Jan. 25, 2024, un...