ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,975, issued on April 14, was assigned to RiceTec Inc. (Alvin, Texas).
"Compositions and methods for modifying genomes" was invented by Matthew Begemann (St. Louis) and Benjamin Neil Gray (St. Louis).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods for modifying genomic DNA sequences are provided. The methods produce double-stranded breaks (DSBs) at pre-determined target sites in a genomic DNA sequence, resulting in mutation, insertion, and/or deletion of DNA sequences at the target site(s) in a genome. Compositions comprise DNA constructs comprising nucleotide sequences that encode a Cms1 protein operably linked to a promoter ...