US Patent Issued to REGENXBIO on Oct. 6 for "Methods of manufacturing microdystrophin gene therapy constructs" (Maryland, New Jersey, Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,752,021, issued on Oct. 6, was assigned to REGENXBIO INC. (Rockville, Md.).

"Methods of manufacturing microdystrophin gene therapy constructs" was invented by Chunping Qiao (Rockville, Md.), Devin McDougald (Boston), Ye Liu (Clarksville, Md.) and Olivier Danos (Princeton, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are gene constructs and nucleic acids that encode a microdystrophin protein for use in gene therapy and methods of producing recombinant AAV particles containing the nucleic acids. The microdystrophin gene constructs and expression cassettes were engineered for improved therapy with respect to efficacy, potency and safety to t...