ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,766,200, issued on Oct. 20, was assigned to REGENXBIO INC. (Rockville, Md.).

"Treatment of dystrophinopathies with microdystrophin gene therapy constructs" was invented by Chunping Qiao (Rockville, Md.), Devin McDougald (Boston), Ye Liu (Clarksville, Md.) and Olivier Danos (Princeton, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are gene constructs that encode a microdystrophin protein for use in gene therapy. The microdystrophin gene constructs and expression cassettes were engineered for improved therapy with respect to efficacy, potency and safety to the subject when expressed by a viral vector in muscle cells and/or CNS cells."

The ...