ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,156, issued on Sept. 8, was assigned to Regents of the University of Minnesota (Minneapolis).
"Tumor cell-derived exosomes and method of treating colorectal cancer" was invented by Subbaya Subramanian (Minneapolis) and Xianda Zhao (Minneapolis).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides tumor-derived extracellular vesicles (EVs) lacking an immune suppressive factor, for example, miR-424, methods of making and methods of use for treating cancer. Further the present invention provide vaccine compositions comprising modified tumor-derived EVs for use in treating secondary tumors."
The patent was filed on Jan. 15, 2021...