US Patent Issued to Regents of the University of Minnesota on Oct. 6 for "Immortalized keratinocytes, lentivirus for keratinocyte immortalization, and methods of use" (Minnesota Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,388, issued on Oct. 6, was assigned to Regents of the University of Minnesota (Minneapolis).

"Immortalized keratinocytes, lentivirus for keratinocyte immortalization, and methods of use" was invented by Elizabeth Louise Thompson (Minneapolis) and Jakub Tolar (Minneapolis).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are recombinant lentiviral vectors and methods of using the same to produce genetically modified keratinocytes that can be maintained in culture for over 100 population doubling without loss of morphological features or differentiation capacity. Immortalized keratinocytes and immortalized cell lines obtained by the method...