US Patent Issued to Regeneron Pharmaceuticals on Oct. 27 for "Methods of treating multiple myeloma with bispecific anti-BCMA x anti-CD3 antibodies" (New York, New Jersey Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,342, issued on Oct. 27, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Methods of treating multiple myeloma with bispecific anti-BCMA x anti-CD3 antibodies" was invented by Israel Lowy (Dobbs Ferry, N.Y.), David Sternberg (New York), Manish Sharma (Scarsdale, N.Y.) and Lieve Adriaens (Westfield, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "B-cell maturation antigen (BCMA) is expressed on malignant plasma cells. The present invention provides methods for treating multiple myeloma using bispecific antibodies (bsAbs) that bind to both BCMA and CD3 and activate T cells via the CD3 complex in the presence of BCMA-expressing tum...