ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,168, issued on March 31, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Antigen-binding molecules that bind CD38 and/or CD28, and uses thereof" was invented by David DiLillo (New York), Aynur Hermann (New York), Jessica Kirshner (New York), Kara Olson (White Plains, N.Y.), Olga Sineshchekova (Pleasantville, N.Y.), Eric Smith (New York) and Erica Ullman (Yorktown Heights, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "CD38 is expressed on malignant plasma cells. CD28 is a costimulatory molecule required for T-cell activation and survival. Provided herein are novel anti-CD38 antibodies, anti-CD28 antibodies, and bispecific an...