US Patent Issued to REGENERON PHARMACEUTICALS on June 16 for "Complement factor H gene knockout rat as a model of C3 glomerulopathy" (New York Inventors)

ALEXANDRIA, Va., June 16 -- United States Patent no. 12,653,168, issued on June 16, was assigned to REGENERON PHARMACEUTICALS INC. (Tarrytown, N.Y.).

"Complement factor H gene knockout rat as a model of C3 glomerulopathy" was invented by Kishor Devalaraja-Narashimha (Yorktown Heights, N.Y.), Jeffrey D. Lee (New York) and Lori Morton (Chappaqua, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Rat cells and rats comprising an inactivated Cfh locus and methods of making and using such rat cells and rats are provided. The rats comprising an inactivated Cfh locus model C3 glomerulopathy (C3G). Methods are provided for using such rats comprising an inactivated Cfh locus to assess in vivo efficacy of putative C...