ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,523,659, issued on Jan. 13, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Modifying binding molecules to minimize pre-existing interactions" was invented by Giane Oliveira Sumner (Mahwah, N.J.), Jihua Chen (Ossining, N.Y.), Michael Partridge (Eastchester, N.Y.), Albert Torri (Lagrangeville, N.Y.) and Manoj Rajadhyaksha (Colchester, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure is directed towards modifying binding molecules in order to minimize pre-existing binding interactions, including binding molecules engineered to minimize or mitigate background reactivity in a sample matrix caused by drug non-spe...