US Patent Issued to Regeneron Pharmaceuticals on Feb. 17 for "Methods and compositions for targeted genetic modification through single-step multiple targeting" (Maryland, New York Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,553,064, issued on Feb. 17, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Methods and compositions for targeted genetic modification through single-step multiple targeting" was invented by Vera Voronina (North Bethesda, Md.), Lynn Macdonald (Harrison, N.Y.), Brian Zambrowicz (Sleepy Hollow, N.Y.) and Andrew J. Murphy (Croton-on-Hudson, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions are provided for making one or more targeted genetic modifications at a target genomic locus within a cell and for producing non-human animals comprising the modified genomic locus. The methods employ two or more large target...