ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,702, issued on Feb. 10, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Methods for removing undesired components during multistage chromatographic processes" was invented by Travis Tran (Tarrytown, N.Y.), Andrew Tustian (Tarrytown, N.Y.) and Mark Chiboroski (Tarrytown, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "High resolution affinity chromatography combining affinity resolving and affinity capture processes using a single chromatography matrix results in improved resolution between closely related molecular species and significantly enhances overall product yield for large scale commercial production of heterodimeric p...