US Patent Issued to Regeneron Pharmaceuticals on Aug. 25 for "Monospecific antibodies that antagonize leptin receptor" (New York, Massachusetts, New Jersey Inventors)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,715,927, issued on Aug. 25, was assigned to Regeneron Pharmaceuticals Inc. (Tarrytown, N.Y.).

"Monospecific antibodies that antagonize leptin receptor" was invented by Jesper Gromada (Concord, Mass.), Panayiotis Stevis (West Orange, N.J.) and Judith Altarejos (Armonk, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides antibodies and antigen-binding fragments of antibodies that bind to leptin receptor (LEPR), and methods of using the same. According to certain embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that bind LEPR and antagonize LEPR signaling. In certain embodiments, the ...