ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,701, issued on Feb. 10, was assigned to REATA PHARMACEUTICALS INC. (Irving, Texas).

"C4-modified oleanolic acid derivatives for inhibition of IL-17 and other uses" was invented by Melean Visnick (Irving, Texas), Xin Jiang (Coppell, Texas), Martha R. Hotema (Hurst, Texas), Chitase Lee (Ann Arbor, Mich.), Bradley William Caprathe (Livonia, Mich.), William H. Roark (Ann Arbor, Mich.) and Gary L. Bolton (Ann Arbor, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are C4 modified oleanolic acid derivatives of the formula:as well as analogs thereof, wherein the variables are defined herein. In addition, disclosed herein are pharmaceut...