US Patent Issued to RaQualia Pharma on Feb. 17 for "Crystalline forms" (Japanese Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,552,776, issued on Feb. 17, was assigned to RaQualia Pharma Inc. (Aichi, Japan).

"Crystalline forms" was invented by Hideyuki Aoyama (Aichi, Japan), Toyoharu Numata (Aichi, Japan), Masaki Sudo (Aichi, Japan) and Yasuhiro Iwata (Aichi, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to novel crystalline forms of (R)-N-((S)-1-(4-(3,3-dimethyl-2-oxoindolin-1-yl)piperidin-1-yl)-1-oxo-4-phenylbutan-2-yl)piperidine-3-carboxamide hydrochloride (HCl-salt), and to pharmaceutical compositions thereof, process for preparation or isolation of such crystalline forms and compositions, and to methods of using such crystalline forms a...