ALEXANDRIA, Va., May 26 -- United States Patent no. 12,640,231, issued on May 26, was assigned to QUEEN'S UNIVERSITY AT KINGSTON (Kingston, Canada), INSTITUT CURIE (Paris) and INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (Paris).
"Cell-free detection of methylated breast tumor" was invented by Christopher R. Mueller (Kingston, Canada).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is a method for detecting a tumour that can be applied to cell-free samples, to cell-free detect circulating tumour DNA. The method utilizes detection of adjacent methylation signals within a single sequencing read as the basic positive tumour signal, thereby decreasing false positives. The meth...