US Patent Issued to PYRAMID BIOSCIENCES on April 21 for "Methods for preparing tyrosine receptor kinase inhibitors" (Indian, American Inventors)

ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,565, issued on April 21, was assigned to PYRAMID BIOSCIENCES INC. (Waltham, Mass.).

"Methods for preparing tyrosine receptor kinase inhibitors" was invented by Kollol Pal (Needham, Mass.), Prasant Deb (Noida, India), Hari Prakash (Greater Noida, India) and Avinash Borude (Ahmednager, India).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to methods of making pyrazolo[1,5-a]pyrimidine compounds having a structure:via a coupling reaction between an activated pyrazolo[1,5-a]pyrimidine and an amine. The disclosed pyrazolo[1,5-a]pyrimidine compounds can be useful as TRK inhibitors, as further detailed herein. Also disclosed ...