US Patent Issued to Purdue Research Foundation on Sept. 15 for "Generating aorta-gonad-mesonephros-like hematopoietic cells from human pluripotent stem cells under a defined condition" (Indiana Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,679, issued on Sept. 15, was assigned to Purdue Research Foundation (West Lafayette, Ind.).

"Generating aorta-gonad-mesonephros-like hematopoietic cells from human pluripotent stem cells under a defined condition" was invented by Xiaoping Bao (West Lafayette, Ind.) and Yun Chang (West Lafayette, Ind.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention generally relates to a method for producing hematopoietic stem cells and progenitor cells for therapeutic uses through a two-step process manipulating the canonical Wnt signaling pathway. Started from human pluripotent stem cells, the activation of the canonical Wnt signaling pathway ...