ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,165, issued on March 17, was assigned to Purdue Research Foundation (West Lafayette, Ind.).
"Synthesis and composition of amino acid linking groups conjugated to compounds used for the targeted imaging of tumors" was invented by Philip Stewart Low (West Lafayette, Ind.), Sumith A. Kularatne (West Lafayette, Ind.) and Sakkarapalayam M. Mahalingam (West Lafayette, Ind.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a pteroyl ligand that binds to a target receptor protein, ii) a dye molecule, and iii) a linker molecule tha...