US Patent Issued to ProQR Therapeutics II on Feb. 10 for "Single-stranded RNA-editing oligonucleotides" (Dutch Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,911, issued on Feb. 10, was assigned to ProQR Therapeutics II B.V. (Leiden, Netherlands).

"Single-stranded RNA-editing oligonucleotides" was invented by Janne Juha Turunen (The Hague, Netherlands), Petra Geziena De Bruijn (The Hague, Netherlands), Bart Klein (Delft, Netherlands), Roxana Simona Redis (Leiden, Netherlands) and Lenka Van Sint Fiet (Wassenaar, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to antisense oligonucleotides that are capable of bringing about specific editing of a target nucleotide (adenosine) in a target RNA in a eukaryotic cell, wherein said oligonucleotide does not, in itself, form an intr...