ALEXANDRIA, Va., March 31 -- United States Patent no. 12,589,080, issued on March 31, was assigned to Privo Technologies Inc. (Peabody, Mass.).

"Enhanced two-stage microparticle-based localized therapeutic delivery system" was invented by Manijeh N. Goldberg (Newburyport, Mass.), Aaron M. Manzi (Haverhill, Mass.) and Eric R. Goldberg (Newburyport, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A system is disclosed for delivery of a therapeutic agent to a site in mucosal tissue or to the skin of a patient. The system includes a porous mucoadhesive, freeze-dried matrix formed by a composition including chitosan in an aqueous salt solution of a chloride salt of a monovalent cation. The system further inc...