US Patent Issued to President and Fellows of Harvard College on March 17 for "Small molecule modulators of gut bacterial bile acid metabolism" (Massachusetts Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,273, issued on March 17, was assigned to President and Fellows of Harvard College (Cambridge, Mass.).

"Small molecule modulators of gut bacterial bile acid metabolism" was invented by Abigail Sloan Devlin (Cambridge, Mass.) and Arijit Adhikari (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods and compositions related to inhibiting bile salt hydrolase (BSH) and uses thereof. Provided herein is a method for treating a metabolic disorder (e.g., diabetes, obesity), gastrointestinal disease (e.g., a gastrointestinal infection; inflammatory bowel disease (IBD); appendicitis; Crohn's disease (CD); ulcerative col...