US Patent Issued to President and Fellows of Harvard College on Dec. 30 for "Inhibitors of nicotinamide N-methyltransferase, compositions and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,430, issued on Dec. 30, was assigned to President and Fellows of Harvard College (Cambridge, Mass.).

"Inhibitors of nicotinamide N-methyltransferase, compositions and uses thereof" was invented by Matthew D. Shair (Lexington, Mass.), Daniel E. Jeffries (Lexington, Mass.) and Hanna Tukachinsky (Lexington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compounds and pharmaceutically acceptable salts thereof, which are useful as inhibitors nicotinamide N-methyltransferase (NNIMT). Also disclosed are pharmaceutical compositions comprising a compound disclosed herein. Related methods of treating cancer in a subject and methods of inhi...