ALEXANDRIA, Va., April 21 -- United States Patent no. 12,605,480, issued on April 21, was assigned to President and Fellows of Harvard College (Cambridge, Mass.).

"Tough gel-based drug delivery compositions and methods thereof" was invented by Benjamin Ross Freedman (Brookline, Mass.) and David J. Mooney (Sudbury, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are tough gel compositions that comprise an interpenetrating networks (IPN) hydrogel. The IPN hydrogel comprises a first polymer network (covalently crosslinked) and a second polymer network (ionically crosslinked), at least one therapeutic agent, and a clay material. The tough gel compositions may further include an adhesive pol...