US Patent Issued to President and Fellows of Harvard College, Memorial Sloan-Kettering Cancer Center on Aug. 25 for "5-amino-2-piperidinon-3-yl-1-oxoisoindoline derivatives for degradation of IKZF2 degraders" (Massachusetts, New York Inventors)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,715,853, issued on Aug. 25, was assigned to President and Fellows of Harvard College (Cambridge, Mass.) and Memorial Sloan-Kettering Cancer Center (New York).

"5-amino-2-piperidinon-3-yl-1-oxoisoindoline derivatives for degradation of IKZF2 degraders" was invented by Christina M. Woo (Cambridge, Mass.), David K. Miyamoto (Cambridge, Mass.), Michael Kharas (New York) and Sun Mi Park (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds that promote targeted degradation of IKZF2, a protein whose activity is implicated in the pathology of certain cancers (e.g., acute myeloid leukemia). Also provided are pharmaceutical compo...