US Patent Issued to Precision BioSciences on April 7 for "Treatment of retinitis pigmentosa using improved engineered meganucleases" (North Carolina Inventors)

ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,469, issued on April 7, was assigned to Precision BioSciences Inc. (Durham, N.C.).

"Treatment of retinitis pigmentosa using improved engineered meganucleases" was invented by Victor Bartsevich (Durham, N.C.), Derek Jantz (Durham, N.C.), James Jefferson Smith (Morrisville, N.C.) and Michael G. Nicholson (Chapel Hill, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are recombinant meganucleases engineered to bind and cleave a recognition sequence present in a mutant RHO P23H allele. The invention further relates to the use of such recombinant meganucleases in a method for treating retinitis pigmentosa, wherein the mutant RHO P23H allele ...