ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,708,630, issued on Aug. 18, was assigned to PINOTBIO Inc. (Suwon-si, South Korea).

"Combined therapy of 4'-thio-5-aza-2'-deoxycytidine and Venetoclax" was invented by Doo-young Jung (Suwon-si, South Korea), Jin-soo Lee (Suwon-si, South Korea), Hyun-yong Cho (Suwon-si, South Korea) and Young-hwa Chun (Suwon-si, South Korea).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the combination therapy of 4'-thio-5-aza-2'-deoxycytidine (Aza-T-dCyd), a multi-target inhibitor including a DNMT1 inhibitor, and Venetoclax, an inhibitor of BCL-2, which mediates apoptosis."

The patent was filed on April 5, 2022, under Application No. 18/...