ALEXANDRIA, Va., July 14 -- United States Patent no. 12,679,896, issued on July 14, was assigned to PIERRE FABRE MEDICAMENT (Boulogne-Billancourt, France).
"Anti-cMET antibody" was invented by Liliane Goetsch (Ayze, France), Thierry Wurch (Machilly, France) and Cedric Bes (Nantes, France).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a novel antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region.The invention also relates to a composition comprising such an antibody antagonist to c-Met and its u...