US Patent Issued to Pharmacosmos Holding on March 3 for "Substituted 1',2'-dihydro-3'h-spiro[cyclohexane-1,4'-pyrimido[5',4':4,5pyrrolo[2,1-c [1,2,4triazin-3'-ones as cyclin-dependent kinase inhibitors" (North Carolina Inventor)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,502, issued on March 3, was assigned to Pharmacosmos Holding A/S (Holbaek, South Korea).

"Substituted 1',2'-dihydro-3'h-spiro[cyclohexane-1,4'-pyrimido[5',4':4,5pyrrolo[2,1-c [1,2,4triazin-3'-ones as cyclin-dependent kinase inhibitors" was invented by Jay Copeland Strum (Hillsborough, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention is in the area of cell cycle inhibiting compounds for the treatment of disorders involving abnormal cellular proliferation, and include selective CDK2 inhibitors for medical therapy and their pharmaceutically acceptable salts and compositions. The inhibitors are pyrimidine-based N-heterocyclic compounds...