US Patent Issued to Pfizer on Aug. 4 for "Crystalline form of a SHP2 inhibitor" (Colorado Inventors)

ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,698,271, issued on Aug. 4, was assigned to Pfizer Inc. (New York).

"Crystalline form of a SHP2 inhibitor" was invented by Katie Keaton Brown (Niwot, Colo.) and Aaron Keith Goodwin (Golden, Colo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This Invention relates to a hemihydrate crystalline form of (S)-1'-(6-((2-amino-3-chloropyridin-4-yl)thio)-1,2,4-triazin-3-yl)-1,3-dihydrospiro[indene-2,4'-piperidin]-1-amine free base (Form 1). The invention also relates to pharmaceutical compositions comprising this crystalline form, and to methods of using the crystalline form and such compositions for the treatment of abnormal cell growth, such as cancer, in a ma...