US Patent Issued to PERSONAL GENOME DIAGNOSTICS on Nov. 3 for "Synthetic polynucleotides and method of use thereof in genetic analysis" (Maryland Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,266, issued on Nov. 3, was assigned to PERSONAL GENOME DIAGNOSTICS INC. (Baltimore).

"Synthetic polynucleotides and method of use thereof in genetic analysis" was invented by John Thompson (Baltimore), Derek Murphy (Baltimore), Gustavo Cerqueira (Baltimore), Cindy Maddox (Baltimore) and Laurel Keefer (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure provides a synthetic standard which includes polynucleotides (e.g., DNA or RNA) containing multiple clinically important germline and somatic variants. These materials are utilized to calibrate, evaluate, and/or validate the performance of polynucleotide-based genetic analysis assay...