US Patent Issued to Peking University on March 17 for "Senolytic and antiinflammatory prodrugs and methods of use thereof" (Chinese Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,576,155, issued on March 17, was assigned to Peking University (Beijing).

"Senolytic and antiinflammatory prodrugs and methods of use thereof" was invented by Hongkui Deng (Beijing), Tuoping Luo (Beijing), Yusheng Cai (Beijing), Huanhuan Zhou (Beijing), Yinhua Zhu (Beijing), Jingjing Zhao (Beijing), Jiebin Dong (Beijing) and Honggang Li (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "Senolytic and anti-inflammatory prodrugs are provided, which are designed from a cytotoxic agent, by chemically modifying the cytotoxic agent to incorporate a site cleavable by SA-Beta-gal following delivery of the prodrug in vivo, to release the active parent drug...