US Patent Issued to PAUL SCHERRER INSTITUT on Oct. 27 for "Transglutaminase conjugation method with a glycine based linker" (Swiss Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,773,460, issued on Oct. 27, was assigned to PAUL SCHERRER INSTITUT (Villigen PSI, Switzerland).

"Transglutaminase conjugation method with a glycine based linker" was invented by Roger Schibli (Baden, Switzerland), Martin Behe (Gelterkinden, Switzerland), Philipp Spycher (Zurich, Switzerland), Julia Frei (Brugg, Switzerland) and Jori Wehrmuller (Zurich, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for generating an antibody-payload conjugate by means of a microbial transglutaminase (MTG). The method comprises a step of conjugating a linker comprising or having the peptide structure (shown in N-less ...