US Patent Issued to Paragon Therapeutics on July 7 for "PD-1 binding proteins, VEGF and PD-1 bispecific binding proteins, compositions, and methods of use" (Massachusetts Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,997, issued on July 7, was assigned to Paragon Therapeutics Inc. (Waltham, Mass.).

"PD-1 binding proteins, VEGF and PD-1 bispecific binding proteins, compositions, and methods of use" was invented by Byong Ha Kang (Waltham, Mass.), Hussam Hisham Shaheen (Waltham, Mass.), Gopalan Raghunathan (Waltham, Mass.), Ghassan Najib Fayad (Waltham, Mass.) and Mohammad Murshid Alam (Waltham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Bispecific antibodies that bind VEGF and PD-1, pharmaceutical compositions thereof, and methods of use thereof, including methods of inhibiting VEGF and PD-1 biological activities."

The patent was filed on Dec. 15, 2025, ...