ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,858, issued on July 21, was assigned to Palleon Pharmaceuticals Inc. (Waltham, Mass.).

"Recombinant human sialidases, sialidase fusion proteins, and methods of using the same" was invented by Li Peng (Lexington, Mass.), Lizhi Cao (Stoneham, Mass.) and Lihui Xu (Chestnut Hill, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates generally to recombinant human sialidases and recombinant sialidase fusion proteins, wherein the sialidase optionally contains one or more mutations compared to wild-type human sialidase, e.g., a substitution, deletion, or addition of at least one amino acid. The invention also provides antibody conjugat...