US Patent Issued to Pairwise Plants Services on May 19 for "Compositions and methods for RNA-encoded DNA-replacement of alleles" (North Carolina Inventors)

ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,833, issued on May 19, was assigned to Pairwise Plants Services Inc. (Durham, N.C.).

"Compositions and methods for RNA-encoded DNA-replacement of alleles" was invented by Joseph Matthew Watts (Cary, N.C.), Aaron Hummel (Hillsborough, N.C.), Yongjoo Kim (Chapel Hill, N.C.), Shai Joshua Lawit (Durham, N.C.) and David Schwark (New Hill, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to recombinant nucleic constructs comprising Type II CRISPR-Cas effector proteins, reverse transcriptases and extended guide nucleic acids and methods of use thereof for modifying nucleic acids in plants."

The patent was filed on Jan. 26, 2024, u...