US Patent Issued to PACKGENE BIOTECH on Nov. 11 for "Helper plasmid and method for preparing recombinant adeno-associated virus" (Chinese Inventors)

ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,466,858, issued on Nov. 11, was assigned to PACKGENE BIOTECH Co. LTD. (Guangzhou, China).

"Helper plasmid and method for preparing recombinant adeno-associated virus" was invented by Huapeng Li (Guangdong, China), Jia Liu (Guangdong, China) and Wanwen Xie (Guangdong, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides a helper plasmid for preparing a recombinant adeno-associated virus (rAAV), including: 1) a coding sequence of an AAV Rep protein and a coding sequence of an AAV Cap protein; 2) at least one promoter sequence; and 3) at least one DA'sequence or AD' sequence, wherein the AD' sequence is a reverse complement...