ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,391, issued on May 12, was assigned to Pacific Biosciences of California Inc. (Menlo Park, Calif.).
"Cyanine dyes" was invented by Stephen Yue (Eugene, Ore.), Gene Shen (Santa Clara, Calif.) and Wei-Chuan (David) Sun (Mountain View, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a novel class of cyanine dyes that are functionalized with sulfonic acid groups and a linker moiety that facilitates their conjugation to other species and substituent groups which increase the water-solubility, and optimize the optical properties of the dyes. Also provided are conjugates of the dyes, methods of using the dyes and their conjugate...