ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,294, issued on March 31, was assigned to OXFORD UNIVERSITY INNOVATION Ltd. (Oxford, Great Britain).

"Process for producing cardiomyocytes" was invented by Ming Lei (Oxford, Great Britain), Derek Terrar (Oxford, Great Britain) and Faizzan Ahmad (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a process for producing a population of cells which comprises mature atrial cardiomyocytes. The process comprises the step of treating iPS cells according to a treatment regimen which comprises contacting the iPS cells with Gremlin2 and retinoic acid, such that at least a portion of the iPS cells differentiate into matur...