US Patent Issued to Oxford Genetics on Sept. 9 for "Inducible AAV system comprising cumate operator sequences" (British Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,443, issued on Sept. 9, was assigned to Oxford Genetics (Oxfordshire, Great Britain).

"Inducible AAV system comprising cumate operator sequences" was invented by Ryan Cawood (Oxford, Great Britain), Tom Payne (Oxford, Great Britain) and Alissa Bray (Oxford, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to nucleic acid molecules, vectors and plasmids comprising AAV cap genes and rep genes, wherein the cap and rep genes are both operably-associated with an inducible promoter which comprises one or more cumate operator (CuO) sequences. The invention further relates to producer and packaging cell lines which are use...