ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,474,337, issued on Nov. 18, was assigned to OSAKA UNIVERSITY (Suita, Japan).
"Therapeutic agent for autoimmune diseases or allergy, and method for screening for the therapeutic agent" was invented by Atsushi Kumanogoh (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a therapeutic agent for treating a cellular immune disease, comprising as an active ingredient a substance that inhibits binding between Sema3A and a Neuropilin-1/Plexin-A1 heteroreceptor. The substance includes, for example, a Sema3A neutralizing antibody, a Neuropilin-1 neutralizing antibody, or a soluble Neuropilin-1 or derivative thereof. Also disclosed is a meth...