US Patent Issued to OrthoTrophix on May 12 for "Hard tissue therapeutics" (California, Texas Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,622,945, issued on May 12, was assigned to OrthoTrophix Inc. (Oakland, Calif.).

"Hard tissue therapeutics" was invented by Yoshinari Kumagai (Foster City, Calif.), Dawn McGuire (Orinda, Calif.), Meghan Miller (Antioch, Calif.) and David Rosen (New Braunfels, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds, pharmaceutical compositions, and a method of treating hard tissue diseases and disorders are disclosed. The compounds may be a peptide and is structured to bind integrin AlphavBeta3 expressed by osteocytes and by selective binding to the cell surface integrin on hard tissue forming cells regulate three-dimensional bone shape, cartilage f...