ALEXANDRIA, Va., March 24 -- United States Patent no. 12,582,658, issued on March 24, was assigned to Oregon Health & Science University (Portland, Ore.) and PDX Pharmaceuticals Inc. (Portland, Ore.).

"Therapeutic constructs for co-delivery of anti-cancer agent(s) and immune checkpoint inhibitor(s)" was invented by Wassana Yantasee (Lake Oswego, Ore.), Moataz Reda (Portland, Ore.) and Worapol Ngamcherdtrakul (Portland, Ore.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are therapeutic constructs including a delivery particle, at least one anti-cancer agent (e.g., a mitotic kinase inhibitor), and at least one immune checkpoint inhibitor. Also disclosed are therapeutic constructs including a ...