ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,689, issued on Feb. 10, was assigned to ONCODESIGN PRECISION MEDICINE (Dijon, France).

"Macrocyclic LRRK2 kinase inhibitors" was invented by Petra Marcella Blom (Destelbergen, Belgium), Christopher Gaetan Housseman (Massy, France), Alain Daugan (Vaugrigneuse, France), Audrey Dumoulin (Antony, France), Maxime Laugeois (Paris), Alexis Denis (Paris), Nicolas Faucher (Suresnes, France), Iuliana Botez (Rueil Malmaison, France), Arnaud Le Tiran (Croissy sur Seine, France), Kenneth Christensen (Copenhagen, Denmark) and Yann Lamotte (Antony, France).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of Formula (I): wherein R, X1, X2, X3, Z1, Z2, Z3, A ...